Last Updated on December 10, 2025 by Simran
Choosing to pursue B.Tech Biotechnology in 2025 opens the door to one of India’s fastest-growing engineering fields, blending biology, chemistry, and technology to create solutions in healthcare, agriculture, genetics, and environmental science. Admission to top biotechnology colleges is primarily driven by performance in various entrance exams conducted at the national, state, and university levels. These exams assess a student’s understanding of core subjects like Physics, Chemistry, Mathematics, and in some cases Biology, making early preparation essential for securing a strong rank.
In 2025, aspirants can choose from several major pathways including JEE Main, state engineering entrance tests, and institution-specific exams such as VITEEE, SRMJEEE, and BITSAT. Each exam has its own pattern, eligibility criteria, and level of competition, offering multiple opportunities for students from both PCM and PCB backgrounds.
This blog provides a comprehensive overview of all key entrance exams for B.Tech Biotechnology in India in 2025 to help students plan their admissions journey effectively.
Key Highlights of B.Tech Biotechnology Entrance Exams 2025
| Exam | Course | Seats (Approx.) | Exam Date (Tentative) | Application Month |
| JEE Main 2025 | B.Tech Biotechnology | 10,000+ (NITs, IIITs) | Jan & Apr 2025 | Nov 2024–Jan 2025 |
| JEE Advanced 2025 | B.Tech Biotechnology (IITs) | 500+ (IIT Delhi, Kharagpur) | May/Jun 2025 | May 2025 |
| CUET UG 2025 | B.Tech Biotechnology | 5,000+ (Central Universities) | May 2025 | Feb–Mar 2025 |
| VITEEE 2025 | B.Tech Biotechnology | 1,000+ (VIT Vellore) | Apr 2025 | Dec 2024–Mar 2025 |
| SRMJEEE 2025 | B.Tech Biotechnology | 800+ (SRM Institutes) | Apr–Jun 2025 | Nov 2024–Apr 2025 |
| COMEDK UGET 2025 | B.Tech Biotechnology | 2,000+ (Karnataka Colleges) | May 2025 | Feb–Apr 2025 |
| State CETs (e.g., MHT CET, KCET) | B.Tech Biotechnology | 5,000+ (State Quotas) | Apr–May 2025 | Jan–Mar 2025 |
Top National & University-Level Entrance Exams 2025
Major national exams include JEE Main, JEE Advanced, CUET UG, VITEEE, and SRMJEEE. Each exam covers Physics, Chemistry, and either Maths or Biology, depending on the institute’s eligibility rules. Students must track application deadlines, exam modes, and participating colleges to optimize their admission strategy. State-level CETs such as MHT CET, KCET, and TS EAMCET also offer significant seat availability for biotech aspirants within state quota.
1. Joint Entrance Examination (JEE Main)
- Conducting Body: National Testing Agency (NTA)
- Courses: B.Tech Biotechnology in NITs, IIITs, GFTIs, and state colleges
- Participating Institutes: NIT Durgapur, NIT Raipur, Anna University, etc.
- Exam Mode: Online (CBT)
- Duration: 3 hours
- Total Questions: 90 (75 to attempt)
- Marking: +4 for correct, -1 for incorrect
- Sections: Physics (25Q), Chemistry (25Q), Maths (25Q) or Biology (optional for some states)
- Application Fee: ₹1000 (General), ₹800 (SC/ST)
JEE Main is the gateway for 80% of B.Tech Biotechnology seats outside IITs. For 2025, Session 1 is in January, Session 2 in April. Top rankers (under 50,000) secure seats in premier NITs. Biology option is available in some state quotas for PCB students.
2. Joint Entrance Examination (JEE Advanced)
- Conducting Body: IIT Kanpur (for 2025)
- Courses: B.Tech Biotechnology in IITs (Delhi, Kharagpur, Madras, etc.)
- Seats: Limited (e.g., IIT Delhi: 40 seats)
- Exam Mode: Online
- Duration: 3 hours (2 papers)
- Total Questions: 54 (variable types: MCQ, numerical)
- Sections: Physics, Chemistry, Maths/Biology (PCB for biotech)
- No negative marking for numerical answers
Only top 2.5 lakh JEE Main qualifiers can appear. JEE Advanced 2025 focuses on advanced problem-solving. IIT Kharagpur’s biotech programme is renowned for research in genetic engineering.
3. Common University Entrance Test (CUET UG)
- Conducting Body: NTA
- Accepted by: BHU, DU, JNU, AMU for B.Tech Biotechnology
- Exam Mode: Online
- Duration: 45-60 minutes per subject
- Sections: Domain (Biology/Chemistry/Physics), General Test, Language
- Questions: 50 per domain (40 to attempt)
- Marking: +5 correct, -1 incorrect
CUET 2025 is ideal for central universities. BHU’s biotech seats via CUET emphasize integrated research. Application starts February 2025.
4. VIT Engineering Entrance Examination (VITEEE)
- Conducting Body: Vellore Institute of Technology
- Courses: B.Tech Biotechnology at VIT Vellore/Chennai
- Exam Mode: Online (remote proctored)
- Duration: 2.5 hours
- Total Questions: 125
- Sections: Maths/Biology (40Q), Physics (35Q), Chemistry (35Q), English/Aptitude (15Q)
- No negative marking
- Application Fee: ₹1350
VITEEE 2025 offers scholarships based on ranks (under 1,000 for full tuition waiver). Strong focus on biology for biotech aspirants.
5. SRM Joint Engineering Entrance Examination (SRMJEEE)
- Conducting Body: SRM Institute of Science and Technology
- Campuses: Chennai, Delhi-NCR, Sonepat
- Exam Mode: Online
- Duration: 2.5 hours
- Total Questions: 125
- Sections: Physics (35Q), Chemistry (35Q), Biology/Maths (40Q), English (15Q)
- Marking: +1 correct, no negative
SRMJEEE 2025 has three phases (Apr-Jun). SRM Chennai’s biotech lab is equipped for pharma research.
6. Other Important State & University Exams
State CETs offer thousands of seats in government and private engineering colleges. Popular exams include:
| MHT CET 2025 | Maharashtra colleges (e.g., ICT Mumbai) |
| TS EAMCET 2025 | Telangana universities |
| AP EAMCET 2025 | Andhra Pradesh colleges |
| COMEDK UGET 2025 | Karnataka private colleges |
| KCET 2025 | Karnataka government seats |
| WBJEE 2025 | West Bengal engineering colleges |
| KEAM 2025 | Kerala engineering seats |
| ICAR AIEEA UG 2025 | Agricultural biotech in ICAR institutes |
Syllabus Comparison (Major Exams)
The syllabus for biotechnology-oriented entrance exams largely revolves around NCERT Class 11–12 fundamentals. However, each exam varies in the number of questions, overall weightage, and the inclusion of Maths or Biology. While JEE Main focuses purely on PCM, exams like VITEEE, SRMJEEE, and CUET allow students to choose between Maths or Biology, making them more accessible to PCB students as well.
Syllabus Overview Table
| Topic | JEE Main | VITEEE | SRMJEEE | CUET UG |
|---|---|---|---|---|
| Physics | 25 questions (Class 11–12 NCERT) | 35 questions | 35 questions | 50 questions (Domain section) |
| Chemistry | 25 questions | 35 questions | 35 questions | 50 questions |
| Maths/Biology | 25 questions (Maths only) | 40 questions (Maths/Biology) | 40 questions (Maths/Biology) | 50 questions (Biology Domain) |
| English/Aptitude | Not included | 15 questions | 15 questions | General Test |
Key Takeaways
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JEE Main is the most PCM-intensive exam with no biology component.
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VITEEE and SRMJEEE give flexibility to PCB students by allowing Biology instead of Maths.
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CUET UG focuses strongly on biology for students targeting central universities offering B.Tech Biotechnology.
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Physics and Chemistry remain common and crucial across all exams.
Expected Cut-off 2025 (General Category)
Cut-offs depend on exam difficulty, seat availability, and the reputation of the institute. For 2025, the expected benchmarks indicate increasing competition, especially for premier biotechnology colleges in India.
Expected Cut-offs Table
| Exam | College | Expected Cut-off (General Category) |
|---|---|---|
| JEE Main | NIT Durgapur (Biotechnology) | 95–98 percentile |
| JEE Advanced | IIT Kharagpur (Biotechnology) | 150–200 marks |
| VITEEE | VIT Vellore | Rank under 10,000 |
| SRMJEEE | SRM Chennai | 90–95 percentile |
| CUET UG | BHU | 600–700/800 |
| COMEDK | RV College of Engineering | 120–140 marks |
Insights
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IIT seats remain extremely competitive, requiring top performance in both JEE Main and JEE Advanced.
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VIT and SRM see rising demand, pushing cut-offs higher every year.
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CUET cut-offs vary widely based on domain marks and college preferences.
Preparation Strategy for B.Tech Biotechnology Entrance Exams 2025
A well-structured preparation plan is essential because biotechnology aspirants appear for multiple exams with overlapping but varied syllabi. Starting early and maintaining conceptual clarity is key.
Step-by-Step Preparation Plan
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Start 8–10 months early, giving enough time to cover NCERT thoroughly—especially for Physics, Chemistry, and Biology.
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Read newspapers daily (The Hindu/Indian Express) if your exam includes general aptitude or current affairs sections.
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Solve 5–10 previous years’ papers weekly from January to understand question patterns and improve accuracy.
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Strengthen Biology concepts such as genetics, molecular biology, evolution, and microbiology for exams offering the bio option.
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Join coaching like FIITJEE, Allen, or trusted online platforms (Unacademy, BYJU’S) for structured guidance.
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Take weekly mock tests starting March, and continuously track mistakes—especially in weak areas like Physical Chemistry or advanced Physics.
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Balance PCB/PCM requirements, keeping in mind that Maths boosts your selection chances in many engineering colleges.
Additional Tips
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Make formula charts for revision.
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Study NCERT line-by-line for Biology and Chemistry.
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Practice numerical problems daily for Physics and Maths.
Best Books for Entrance Exams Preparation
| Subject | Recommended Books |
|---|---|
| Physics | • HC Verma – Concepts of Physics (Vol 1 & 2)• DC Pandey – Physics for JEE |
| Chemistry | • OP Tandon – Physical, Organic & Inorganic Chemistry• NCERT Chemistry Class 11 & 12 |
| Biology | • Trueman’s Elementary Biology (Vol 1 & 2)• NCERT Biology Class 11 & 12 |
| Mathematics | • RD Sharma – Objective Mathematics• Arihant Publications – JEE Maths Series |
| Practice Guides | • MTG – 40 Years JEE Question Bank• Disha Publications – CUET Biology Guide |
| Aptitude (If Required) | • RS Aggarwal – Quantitative Aptitude |
Important Dates to Remember (Tentative)
| Exam | Expected Dates (2025) |
|---|---|
| JEE Main Session 1 | Jan 24 – Feb 1, 2025 |
| JEE Advanced | May 18, 2025 |
| CUET UG | May 8 – Jun 1, 2025 |
| VITEEE | Apr 21 – 27, 2025 |
| SRMJEEE Phase 1 | Apr 22 – 27, 2025 |
| COMEDK UGET | May 10, 2025 |
FAQs
1. Which entrance exam is required for B.Tech Biotechnology in India?
Most students appear for exams like JEE Main, state engineering tests, or institute-level exams such as VITEEE, SRMJEEE, and BITSAT, providing multiple pathways to biotechnology colleges.
2. Is JEE Main mandatory for B.Tech Biotechnology admission?
JEE Main is not mandatory, but it is preferred by top engineering institutes and NITs. Students can also opt for private or state-level exams for admission.
3. Can PCB students apply for B.Tech Biotechnology in 2025?
Yes, several universities allow PCB students to apply, especially through exams like VITEEE, SRMJEEE, and CUET. However, JEE Main generally requires Mathematics.
4. What subjects are important for biotechnology entrance exams?
Most exams focus on Physics, Chemistry, Mathematics, and sometimes Biology. Strong conceptual understanding and analytical skills are essential for securing good ranks.
5. Which exam is the easiest for B.Tech Biotechnology admission?
There is no universally “easy” exam, but VITEEE and SRMJEEE are often considered more manageable compared to JEE Main, depending on a student’s preparation.
6. Do all engineering entrance exams include Biology for biotechnology aspirants?
No, many engineering entrance exams only test PCM. However, certain private universities include Biology sections to support PCB students applying for biotechnology.
7. Is CUET a valid exam for B.Tech Biotechnology in central universities?
Yes, CUET is accepted by several central universities offering biotechnology, making it a good option for students seeking non-engineering entrance routes.
8. What is the level of competition in biotechnology entrance exams?
Competition varies by exam, but popular tests like JEE Main and BITSAT are highly competitive due to large applicant numbers and limited high-rank seats.
9. Are there state-level exams for B.Tech Biotechnology in India?
Yes, states like Maharashtra, Karnataka, West Bengal, and Uttar Pradesh conduct engineering entrance exams that include biotechnology seats in participating colleges.
10. How should students prepare for biotechnology entrance exams in 2025?
Students should follow a structured study plan, practice mock tests regularly, revise NCERT concepts thoroughly, and stay updated with exam notifications and syllabus changes.